Aerial view of UCSD campus looking South
Geisel Library - Nobel Laureates at UCSD
Discovery of new atmospheric reaction garners prize
Natural Sciences Building
The crystal structure of a group II intron in the pre-catalytic state
Structure of an inhibitor of hepatitis C virus protein synthesis bound to its target in the viral ribonucleic acid (RNA) genome
ANCA probe staining amyloid plaques derived from Alzheimer’s-related Aβ peptides fluoresces as green and as yellow when derived from prion proteins (PrPSC)
Generation of bio-resistive surface coatings on amyloids inhibits harmful protein-amyloid interactions associated with Alzheimer disease
Proposed schematic models of the interfacial binding surface of four different members of the Phospholipase A2 superfamily
Urey Hall and Pacific Hall
Characterization of the "inhibitor binding pocket" in the catalytic domain of the calcium-independent phospholipase A2 with residues within a 5 A raidus of the inhibitor shown
A Crystalline Singlet Phosphinonitrene: a Nitrogen Atom Transfer Agent
Drug candidate in orange envelope bound to UPPS
Possible binding modes for phospholipase A2 via its membrane interaction site, another allosteric site, and its catalytic site
Researchers from Professor Neal Devaraj’s Lab and The BioCircuits Institute have designed and synthesized the first artificial cell membrane capable of sustaining continual growth, just like a living cell. The artificial cell membrane continually synthesizes all of the components needed to form additional catalytic membranes mimicking nature’s ability to support phospholipid membrane formation. To develop the growing membrane the researchers substituted a complex network of biochemical pathways with a single autocatalyst that simultaneously drives membrane growth. Their achievement provides an important new tool for synthetic biology and origin of life studies. Their research paper was published in the 6/22/15 early edition of the Proceedings of the National Academy of Sciences. Congratulations to the Devaraj Lab and The BioCircuits Institute! To access the full research report click here
Professor Nathan Gianneschi and Chair Seth Cohen of UC San Diego's Department of Chemistry and Biochemistry co-led a team of researchers from UC San Diego, Florida State and Pacific Northwest National Labs that, for the first time, visualized the growth of nanoscale chemical complexes in real time. The ground-breaking research employed a recently developed process called Liquid Cell Transmission Electron Microscopy (LCTEM) that provided scientists an unprecedented understanding of the stepwise formation of nanostructures. Their research paper was published in the 'Journal of the American Chemical Society' (6/8/2015 online edition). Congratulations to the Gianneschi and Cohen Groups! To read the full research article click here
Structural colors arise from the interaction of light with materials that have patterns on a minute scale. The natural structure of melanosomes (tiny packets of melanin) that produce structural colors in bird feathers inspired the efforts of a team of researchers from UC San Diego (the Gianneschi Group), the University of Akron and Scripps Institution of Oceanography, to fabricate colored films with colors determined by physical structures rather than by pigments.
The team created the colored films by synthesizing various concentrations of polydopamine-based synthetic melanin nanoparticles (SMNPs) that were then evaporated into thin layers that mimicked the natural structures found in bird feathers. The SMNP films interacted with light to create pure hues of color ranging from red to green. The new SMNP materials have broad applicability in colorimetric sensors, full color displays, and photonic pigments. The research team’s findings were documented in a paper published in the 5/26/2015 issue of ‘ACS NANO'. Congratulations to the Gianneschi Group and the entire research team! To access the full research report click here
A survey on faculty diversity at the top 50 U.S. chemical research universities and colleges, ranked UC San Diego’s Chemistry and Biochemistry Department No. 2 in the nation. Minorities hold 11% of the Department’s faculty positions, compared to 16% at No. 1 Georgia Tech and an average of 4% for all 50 institutions (only UC San Diego and Georgia Tech were at or above 10%). The 2013-14 academic year survey was conducted by OXIDE, a collaboration between the National Science Foundation, the National Institutes of Health and the U.S. Department of Energy. An article on the survey, including a discussion on diversity with UC San Diego Associate Professor of Chemistry & Biochemistry, Judy Kim, was published in Chemical & Engineering News (05/18/15 Issue). To read the full survey article click here
The Office of the President has designed the Dissertation Year Fellowship program to identify doctoral candidates: 1) who have overcome educational, social, or economic barriers, or 2) whose research or planned career direction focuses on problems related to disadvantaged segments of society, and 3) who demonstrate strong potential, promise and desire for a university teaching and research career. Dissertation Year Fellowships are awarded to promising students in the final stages of their doctoral work who demonstrate strong potential for university teaching and research. Congratulations to David John Lee (Burkart Lab) on being selected as the recipient of this prestigious award!
Associate Professor of Chemistry and Biochemistry, Michael Tauber, was one of two UC San Diego faculty members to win the campus's 2015 Academic Integrity Faculty Award. The award is presented annually to a faculty member who has contributed significantly to creating a culture of academic integrity through research, teaching and service. Executive Vice Chancellor for Academic Affairs, Suresh Subramani, and Academic Senate Chair, Gerry Boss, presented the award to Professor Tauber at the 5th Annual Integrity Awards Ceremony held late last month. Congratulations Mike!
Erica Lennard, Director of Student Affairs for the Department of Chemistry and Biochemistry, was named a recipient of UC San Diego's 2014-2015 Exemplary Staff Employee of the Year Award (ESEOY). The ESEOY recognizes professional and support staff from across all Vice Chancellor areas and UC San Diego Health Systems, who have demonstrated exemplary service and made exceptional contributions to the UCSD and San Diego communities. Erica was recognized for her outstanding management of all aspects of the Department of Chemistry and Biochemistry's educational enterprise which impacts more than 25,000 students each year. Chancellor Khosla presented Erica with the ESEOY Award at a formal ceremony held on May 19, 2015. Congratulations Erica!